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KMID : 1103720120660010063
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Journal of the Korean Society of Radiology
2012 Volume.66 No. 1 p.63 ~ p.68
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Micro CT Findings on Microcalcification Using a Paraffin Block of Breast Specimens: A Preliminary Study
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Jeon Su-Bin
Jin Gong-Yong
Choi Eun-Jeong
Han Young-Min
Le Jae-A
Chung Myung-Ja
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Abstract
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Purpose: We compared micro CT images with mammography images to evaluate microcalcifications in breast specimens in paraffin blocks.
Materials and Methods : We enrolled 30 patients who had a biopsy of a breast mass that included microcalcifications. We did mammography and micro CT for paraffin blocks of that breast specimen. We evaluated numbers (0, absence; 1, less than 5; 2, 5-10; 3, more than 10) and sizes of microcalcifications. We used the Mann-Whitney test to statistically evaluate differences in the number of microcalcifications between the two imaging methods. We also measured the longest size of the microcalcifications using measurement in PACS.
Results: The proportions of microcalcifications in specimens in paraffin blocks on mammography and micro CT were 10/30 (30%) and 11/30 (36.6%), respectively. The scores for microcalcifications on micro CT and mammography were 0.8 ± 1.2 and 0.73 ± 1.2, respectively (p = 0.8001). The sizes of microcalcifications ranged from 0.1-0.5 mm (mean, 0.25 ± 0.17 mm) on micro CT.
Conclusion: Micro CT may be a new and promising technique to verify the evaluation by mammography of microcalcifications in breast tissue.
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KEYWORD
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X-Ray Microtomography , Microcalcification , Breast
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